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This may indicate that additional layers of regulation exist as compared with cyanobacteria, microalgae or non-vascular plants as often observed for other metabolic pathways

Scripps Clinic obesity and internal medicine specialist Mitch Biermann, MD, PhD, and Scripps Clinic internal medicine resident Michelle Wong, MD, report in the medical journal Obesity that most participants in their small clinical study sustained their peak weight loss from the popular medications even after reducing the dose frequency to once every two weeks and, for some patients, as infrequently as once every six weeks

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Hair loss concerns have also emerged in community discussions, though clinical trial data on this specific side effect is limited