Because GSH status is dynamic, the outcome measures were extended beyond GSH status alone to include 8-OHdG and F2-isoprostanes (F2-isoP), in case a change in oxidation status was exemplified by evidence of reduced oxidation products rather than a change in GSH or GSH:GSSG ratio (i.e., improvement in tissue-level oxidative stress not represented by RBC indices)
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In practice, research populations studied on dual agonist protocols show ~20-22% body weight reduction vs
Carretero Gmez J, Arvalo Lorido JC, Gmez Huelgas R, Garca de Lucas D, Mateos Polo L, Varela Aguilar JM, et al
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