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Blood glucose and HbA1c levels Renal function indicators Gastrointestinal tolerance Importance of Gradual Dose Escalation A stepwise titration approach minimizes gastrointestinal intolerance and improves patient adherence

But it gives me pause because I can't think of a physiologic scenario that would increase your resting heart rate by 10 beats per minute as a positive thing

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All sex steroids are made intracellularly in peripheral tissues by the mechanisms of intracrinology after menopause

doi: 10.3389/fvets.2022.1063169 66