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Best for: All skin types, especially those prone to puffiness

Finan B, Yang B, Ottaway N, Smiley DL, Ma T, Clemmensen C, et al

Both act as GHRH-style signals that cue your pituitary to release its own GH

"We learned when we were there that the tradeoff was the GLP-1 medicines are not included any longer in the health insurance plans for payment, which brought the average costs down tremendously. The final increase from FY26 to FY27 was ultimately around 7% -- a difference of millions of dollars for Pittsfield taxpayers

But there has been concern that they induce loss of muscle and other components of lean body mass along with fat