Side Effects: dizziness, vision changes, headache, weakness, uncontrollable shaking, constipation, abdominal pain, rapid, pounding, irregular heart rhythm, chest pain, shortness of breath, nausea, significant fatigue, swelling of upper or lower extremities, jaundice, and right upper abdominal pain
A second study, conducted by the EMA, analyzed electronic health records investigating the incidence of suicidal and self-injury events in people with type 2 diabetes (T2D)
Hormonal changes may cause cyclical weight variations of 2-5 pounds and affect appetite, fluid retention, and metabolic rate independent of medication effects
TRICARE covers Wegovy, Saxenda, and Zepbound for weight management, but only on TRICARE Prime, Select, and premium-based plans (Reserve Select, Young Adult, Retired Reserve, and CHCBP)
The SELECT cardiovascular outcomes trial (NEJM, 2023) showed a 20% reduction in major adverse cardiovascular events among patients with existing heart disease -- data that no other GLP-1 in this class has yet matched
