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Population studies of GLP-1 users show measurable nutritional deficiencies developing over time

Abels, Improved distribution analysis of cobalamins and cobalamin analogues in human plasma in which the use of thiol-blocking agents is a prerequisite, Clinica Chimica Acta, Volume 131, Issue 3, 15 July 1983, Pages 211-224, ISSN 0009-8981 Thakkar, K., & Billa, G

This study was designed to systematically investigate the cartilage-protective effects of AOD9604, both alone and in combination with HA, using a well-established collagenase-induced OA rabbit model

But if you also supplement with calcium, your best bet is spacing out the doses

Vitamin B12 is an essential water-soluble vitamin that plays an important role in many functions in the body