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EGT deficiency leads to transcriptional downregulation of sidG To further analyze the role of EGT in siderophore production, the transcript levels of selected genes were analysed by Northern analysis during iron starvation and sufficiency with and without H 2 O 2 stress (Fig

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Thus, in the setting of IGF-IR resistance in the pituitary and hypothalamus of acromegaly patients, the negative feedback loop by IGF-I may be defective resulting in further IGF-I elevations