When assessing baseline characteristics by comparator (Additional file 4: Appendix Table S4C), the proportion of subjects with heart failure, other prior CV events and prior insulin use was higher, and mean eGFR was lower, in the placebo and semaglutide groups than in the other comparator groups, driven by the large patient numbers and high baseline CV risk in the CVOTs
So, again, we submitted that several weeks ago
Reasons for GLP-1 discontinuation (e.g., cost, side effects, clinical decision) were not available
Profound cognitive and behavioral issues need to be analyzed according to a sound patient-centred methodology and integrated with lifestyle and pharmaceutical tools
For a 180-pound patient, that's 108 oz per day (about 3.2 liters), divided into hourly intake of 13-14 oz per hour