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Per FDA labeling for Mounjaro and Zepbound, 15 mg once weekly is the maximum maintenance dose, reached by titrating up from a 2.5 mg initiation dose in 2.5 mg steps
Chancey JH et al (2014) Hilar mossy cells provide the first glutamatergic synapses to adult-born dentate granule cells
doi: 10.1007/s10072-015-2245-7 21 WolfovaK.KuceraM.CermakovaP
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Activation of glutamatergic neurotransmission by ketamine: a novel step in the pathway from NMDA receptor blockade to dopaminergic and cognitive disruptions associated with the prefrontal cortex
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