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In research observations, occasional non-specific findings such as mild gastrointestinal disturbance have been noted with oral administration of peptide compounds in general

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IODIDE METABOLISM AND EFFECTS Many patients with Hashimoto's thyroiditis do not respond to injected TSH with the expected increase in RAIU or release of hormone from the gland(81)

These remain the first-line pharmacological treatments supported by robust clinical trial evidence and cost-effectiveness analyses