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The trial evaluated once weekly cagrilintide doses in participants with overweight or obesity and reported dose dependent reductions in body weight at 26 weeks, with the paper describing the treatment as well tolerated in the study setting

A study published in Nutrition suggests that allulose can decrease body fat accumulation in rats with diet-induced obesity

NADPH forms when NAD+ becomes NADP+

This process stimulates GLP-1 production, as gut bacteria ferment soluble fiber into short-chain fatty acids that further enhance GLP-1 secretion (Ld, 2025)