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high school students from 2015 to 2016 declined substantially for e-cigarettes and marginally for combustible tobacco cigarettes, raising questions about whether there is a systematic concordance between e-cigarette and combustible tobacco cigarette use over time in the population
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Additionally, e-cigarette use has been implicated in new onset and exacerbation of pre-existing seizures
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Furthermore, a larger increase in the serum cotinine level was found in mice exposed to tobacco smoke for 24 weeks, which is 4.8-fold higher than those exposed to room air for the same period
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