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Gally CR, Reis GS, Lima EC, Puchana MJ, Adebayo MA, Dotto GL

Current FDA indications are limited to diabetes and obesity, and any addiction-related use would be off-label

The reasons underlying insufficient efficacy of vessel-targeting strategies have been extensively investigated, and include stroma and tumor cell mechanisms of resistance [287, 297]

Benefits: reduced anxiety, improved mood, better motivation, and enhanced learning

In Vitro Assessment of Drug Interactions Dapagliflozin In in vitro studies, dapagliflozin and dapagliflozin 3-O-glucuronide neither inhibited CYP 1A2, 2C9, 2C19, 2D6, or 3A4, nor induced CYP 1A2, 2B6, or 3A4