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17,18,19,20,21 The only phenotypes that were causally associated with HU were gout and kidney disease

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After incubation with secondary antibodies(Seracare, USA) conjugated to horseradish peroxidase, membranes were visualized using an enhanced chemiluminescence system

MC5R: Expressed in multiple tissues, its exact physiological role remains relatively undefined, although it is believed to be involved in exocrine function

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