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This supports the conclusion that it is specifically the glucagon receptor, present in retatrutide but not in tirzepatide, that drives the larger heart rate signal

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Clayton et al

Cleaned FASP eluates were evaporated completely in SpeedVac concentrator (Thermo Fisher Scientific) and transferred into LC-MS vial containing PEG (final concentration 0.001%, v/v) using 25 l of 50% acetonitrile (ACN) with 2.5% formic acid (FA) and 100 l of ACN