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Even the most commonly used antibiotic for SIBO, Rifaximin (Xifaxan) has reported success rates of around 30% in methane-producing subjects, when used on its own

CJC-1295 with DAC is commonly used alone due to its extended half-life and sustained GH elevation

As the causative bacteria die off due to antibiotics, inflammatory agents are released and temporarily worsen symptoms before improvement is noted