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Importantly, TAX6 mediates inhibition cellautonomously: when expressing TAX6 exclusively in the AWA neurons of tax6 mutants, we were able to rescue exact adaptation and pulsatile response (Figs 3 and 4)

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A common titration approach includes: Week 12: 0.3 mg Week 34: 0.6 mg Week 56: 1.2 mg Week 78: 1.8 mg Week 9 and onward: 2.4 mg or higher, based on tolerance and clinical response Always consult a healthcare provider or licensed research facility for actual dosing guidance

Choe, S.-Y

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