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Likewise, we observed that tumor cells grown as 3D spheroids are more resistant to RSL3-induced ferroptosis than their counterpart grown in adherent conditions (Fig

10,11 demonstrated that GSH levels were significantly decreased in the frontal cortex and hippocampus of AD and mild cognitive impairment (MCI) patient groups compared with levels in an age-matched control group

Resistance can be classified into intrinsic resistance, observed from the outset of the therapy, and acquired resistance, observed after an initial positive response to therapy [297]

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