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Additionally, pine bark extract functions as a potent agent in counteracting skin aging caused by sun exposure, while alpha lipoic acid and grape seed extract contribute with their antioxidant properties to protect skin cells from damage

Use cautiously if taking medication for hormone disorders, particularly 5-alpha-reductase inhibitors, as Astaxanthin may inhibit 5-alpha-reductase, preventing the conversion of testosterone to dihydrotestosterone (DHT) leading to decreased libido, gynecomastia, decreased semen quantity during ejaculation, impotence, increased skin pigmentation, hair growth, weight gain, and low mood

Major cytokines secreted by T cells include IL-1, IL-4, IL-6, TGF-, leukoregulin, and IGF-1, while orbital fibroblasts release IL-1, IL-6, IL-8, IL-10, IL-12, MCP-1, and TNF- (114)

These are not FDA-approved as finished products and are not evaluated by the FDA as equivalent to branded medications

Coutzac C, Jouniaux JM, Paci A, Schmidt J, Mallardo D, Seck A, et al