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Real-world clinical experience of semaglutide in secondary care diabetes: A retrospective observational study

Semaglutide led to a significant reduction in HbA1c levels compared to placebo- Patients receiving semaglutide experienced significant weight loss compared to those on placebo PIONEER Trials (Peptide Innovation for Early Diabetes Treatment): The PIONEER (Peptide Innovation for Early Diabetes Treatment) trials were a series of global, randomized, controlled clinical trials that investigated the efficacy, safety, and tolerability of oral semaglutide, a GLP-1 receptor agonist, in patients with type 2 diabetes

If we can avoid it, because oral can raise clotting factors that could put you at risk for adverse outcomes, and it gets metabolized by the liver

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Potential Side Effects and Considerations As with any medication, Semaglutide injections may have side effects, although they are generally well-tolerated