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Deficiencies occur mainly due to malnutrition, malabsorption disorders, or restrictive diets (e.g., vitamin B 12 deficiency in a vegan diet)

Scientists have noted an imbalance in the production and elimination of reactive oxygen species (ROS) which damage vascular tissue (2, 3)

To enhance ferroptosis-based cancer therapy via glucose metabolism modulation, dopamine (DA) and Fe ions were co-coordinated to encapsulate bacterial outer membrane vesicles (OMVs), followed by in situ growth of ultrasmall gold nanoparticles (Au NPs) on the surface to construct a multifunctional nanoplatform (OMV-DFA) [145]

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It can enter the oesophageal epithelial cells and can cause toxic injury to mitochondria and cellular mutations