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After intravenous administration of 10 mg/kg ASD, metabolites M3, M4, and M5 were detected in rat plasma with the systemic exposure lower than M0

Diarrhea Diarrhea affects a significant proportion of patients and can be one of the more disruptive side effects in daily life

Image analysis was performed with Fiji (ImageJ)

13 C NMR (101 MHz, CDCl 3 ) 168.68 (C 2), 134.93134.18 (m, CD 6), 133.80133.00 (m, CD 12), 130.45129.66 (m, CD 12), 118.15 (d, J = 85.7 Hz, C 6), 41.29 (CH 2 2), 38.75 (CH 2 2), 27.95 (CH 2 2), 27.38 (d, J = 17.1 Hz, CH 2 2), 22.64 (d, J = 50.0 Hz, CH 2 2), 22.04 (d, J = 4.4 Hz, CH 2 2)