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Briefly, the process proceeds with the mRNA synthesis of seleno-GPxs by transcription factors followed by in situ synthesis of Sec on a specific set of tRNA designated as tRNA [ser]Sec and its incorporation into the peptide sequence against the termination codon UGA within ribosomal machinery (Fig

[1] [2] Animals may also convert it to vitamin K 2 , variant MK-4

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Nearly 30% of the worlds population (i.e., almost 1.9 billion people) have insufficient iodine intake as measured by median urinary iodine concentrations below 100 g/L (5)

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