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Model 1: Adjusted for age, income, body mass index status, systolic blood pressure, total cholesterol, fasting serum glucose, cigarette smoking, alcohol consumption, physical activity, medication use (aspirin, antihypertensive medication, antidiabetic medication, and statin), number of chronic diseases (hypertension, diabetes, or dyslipidemia), Charlson Comorbidity Index at baseline in never smokers

Given the growing popularity of e-cigarette flavors and the lack of clear scientific evidence on their health effects, this systematic review aims to assess the available scientific evidence on the impact of e-cigarette flavors in animal models and findings from human studies

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