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Nicotine also suppresses insulin output from the pancreas, which means that smokers, especially those with cigarette addiction, are always slightly hyperglycemic (i.e., they have elevated blood sugar level)

[11] Another under-studied brain-health marker is cerebral blood flow: a study of adolescents reported that the effects of nicotine and tobacco products on brain-health markers during this neurodevelopmental period remain largely unknown and examined associations with decline in cerebral blood flow in the anterior cingulate cortex (ACC) and precuneus/posterior cingulate cortex (PCC)

Photobiomodulation and coenzyme Q(10) treatments attenuate cognitive impairment associated with model of transient global brain ischemia in artificially aged mice

That makes FUT less likely in a case like this

Lowering your nicotine strength, vaping less often, and staying hydrated will usually help