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p = 0.009) with an intercept of 0.024 (p = 0.084), indicating no presence of horizontal pleiotropy, and the GCTA-GSMR estimate of 0.74 (95% CI 0.541.02

So: 500mg x 40% (avg absorbed) = about 200mg absorbed nicotine Now compare that to a pack of smokes: One pack = 2030mg absorbed So 200mg absorbed from a vape = roughly 7 to 10 packs of cigarettes Whoa

E-cigarette technologies have evolved over the years, with the introduction of pod-based systems, temperature control devices, nicotine salts, and nicotine pouches

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Between 0.8% and 1.3% of young people who had never smoked were current vapers