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Reynolds also worked to develop a flavor he thought would be more appealing than past products, so created the Camel cigarette, a blend of several different types of tobacco that would come to be called "the American blend"

While we need more research, the early results look promising

For now, researchers and industry representatives are either unlikely bedfellows in a harm-reduction game plan or at odds over the best way forward

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Nuria Roldan and Lea Lara de Maddalena for their invaluable assistance in managing this study