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This concept is supported by another evidence showing that inhibition of adipose tissue lipolysis by adipose-specific ablation of desnutrin prevented ectopic lipid accumulation in the liver even when fed with a HFD (51)
In patients with HBV infection, smoking further increased the HCC risk by 1.4-fold, and even more dramatically, in individuals with HCV infection, the risk of HCC was increased 2.9-fold if there was a history of cigarette smoking [102]
J Environ Public Health (2012) 2012:564930.10.1155/2012/564390 3 HeJGuDWuXReynoldsKDuanXYaoCet alMajor causes of death among men and women in China
Besides, it was discussed that the visceral fat accumulation was related to several pro-inflammatory mediators that might induce not only hepatic steatosis, but also hepatic damage and subsequent liver fibrosis (59)
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