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The Encyclopedia of Chicago notes the original smoke-filled room was in Chicagos Blackstone Hotel, where: A small group of powerful United States senators gathered to arrange the nomination of Warren G

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doi: 10.1038/sj.bjc.6605558 40 MatsumotoMFunamiKTanabeMOshiumiHShingaiMSetoYet al

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The clinical significance of these nonclinical findings is not known, and healthcare providers should balance the benefits of appropriate anesthesia in pregnant women, neonates, and young children who require procedures with the potential risks suggested by the nonclinical data (see WARNINGS, Pediatric Neurotoxicity, PRECAUTIONS, Pregnancy, and Animal Toxicology and/or Pharmacology)