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Endogenous PTHrP plays an important role in fracture healing as demonstrated in an PTHrP haplo-insufficiency model where reduced cartilaginous and bony callus formation was noted together with reduced endochondral and osteoblastic bone formation [229]

Striking differences in GLP-1R trafficking were noted, with robust and equal endocytosis induced by exendin-asp3 and lixi-asp3 when measured by DERET, but very little from the exendin-phe1 or lixi-phe1 (Figure 6D, Supplementary Figure 4C

The participants were all classified as either overweight or having obesity, with an average baseline weight of 248.5 pounds

2004 Apr;63(4):641-6.

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