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Ethics declarations Ethics approval and consent to participate All experimental procedures on mice were approved by Committee on the Ethics of Animal Experiments of Southern Medical University (Permit No

Tobacco smoke Toxic emissions released by tobacco smoke harms the smoker, people and animals around them, and the environment

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E-smoke generation Third generation electronic nicotine delivery systems with refillable and exchangeable tank options were used to generate the E-smoke

The state was trending toward a 0.9% decrease during the first eight months of fiscal 2020, but saw a 7.8% increase in the final four months over the year amidst the onset of the COVID-19 pandemic