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This is consistent with previous literature demonstrating DA covalently binds to guanyl nucleotides leading to DNA unwinding and cellular apoptosis [66]

Cigarettes expose the body to toxins, and nicotine may boost the production of lipids that contribute to NAFLD

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Regarding the impact of smoking on the OE, we previously reported that CS impaired the OE and olfaction by reducing the olfactory progenitor cells and mature ORNs (Ueha et al., 2016a) and that CS delayed regeneration of the OE (Ueha et al., 2016b)