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Nicotine primarily exerts immunomodulatory effects through cholinergic signaling pathways that can dampen inflammatory responses and reduce immune activation (84)

Substance Use Perspective : Chronic use may include daily or near-daily use of alcohol, marijuana, prescription drugs, or illicit substances, often beyond recommended limits

Cytisine pills were more than twice as effective as the placebo at helping people quit smoking, the researchers found, while a number of the trials in the review suggested the drug was similar to varenicline and possibly more effective than nicotine replacement therapy

2020;40(3):BSR20192567

Archived from the original on 4 June 2011