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It is crucial for effector T-cell functions through the regulation of metabolic activity and has been linked with the pathogenesis of several autoimmune diseases (109), including psoriasis (110)

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Clinical and preclinical studies have demonstrated significant effects on body weight reduction and metabolic regulation, generating considerable scientific interest in its potential role both as a standalone therapy and in combination with GLP-1 receptor agonists for obesity and metabolic disease research

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