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For RCTs, because both known and unknown confounders are randomized, they would affect all trial arms equally

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GLP-1 receptor agonists thus have an interesting interaction with nicotine, which can perhaps be used to both lose more weight and promote smoking cessation, explains a researcher involved in the study, Christoffer Clemmensen, Associate Professor, Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen