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Other short-term effects often associated with cocaine abuse include: increased talkativeness reduced inhibition racing thoughts reduced hunger and fatigue anxiety or paranoia hypersensitivity to light, sound, or touch blood vessel constriction pupil dilation (pupils appear larger than normal) muscle twitching elevated blood pressure, heart rate, breathing, and body temperature tremors vertigo Cocaine can also sometimes trigger more serious negative effects including nausea and vomiting, erratic behavior, seizures, psychotic episodes, heart problems, and even sudden death

Larger doses of amphetamine may impair cognitive function and induce rapid muscle breakdown