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Getting that nicotine level right is honestly one of the most critical steps in a successful switch

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With the right combination of medication, behavioral support, triggers management and social reinforcement, the goal of quitting becomes achievable and the benefits both immediate and long-term are substantial

[17] Since CYP2A6 activity differs by sex (estrogen induces CYP2A6) and genetic variation, cotinine accumulates in individuals with slower CYP2A6 activity, resulting in substantial differences in cotinine levels for a given tobacco exposure

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