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They included significantly lower 18:3-bearing lipids overall ( p = 0.0002, Fishers combined test) and particularly in DAGs ( p = 1 10 10 ) and TAGs ( p = 0.0002)
216 (Springer Publishing Company, 2016)
Clinically, many late-onset MADD patients respond dramatically to high-dose riboflavin (100400 mg/day), confirming residual enzyme function amenable to cofactor restorationclassifying MADD as a prototype FAD-responsive metabolic myopathy (70)
Keywords Glutathione, network pharmacology, heart failure, myocardial infarction Heart Failure (HF) is one of the leading causes of morbidity and mortality worldwide, affecting at least 26 million people globally with annual mortality rate of over 50 % in the end-stage group[1,2]
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