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As published in the American Journal of Epidemiology , Reifs research was the first scientific proof that dogs can also suffer cancer risks from cigarette smoke

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The constricting effects of nicotine on blood vessels can significantly reduce blood flow to the nipple area, leading to potential complications

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Moreover, high TSLP production leads to activation and migration of Langerhans cells from the epidermis toward the dermis and an increase of activated DCs in the dermis (van Splunter et al., 2020)