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Key findings from this research include: Improvement in depressive symptoms This 2024 review found evidence that GLP-1 medications may help reduce symptoms of depression

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In previous clinical trials, since depression was not the primary prespecified outcome, most of them did not systematically track mood changes, which may lead to an underestimation of the real risk of adverse mental events during the clinical trial stage [28, 29]

Enhancement of impaired olfactory neural activation and cognitive capacity by liraglutide, but not dapagliflozin or acarbose, in patients with type 2 diabetes: A 16-week randomized parallel comparative study