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[31] [10] However, older adolescents have a reduced risk of initiation smoking with reasoning stemming around an older adolescent being less susceptible than a younger adolescent in engaging in the initial smoking process

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Other oxidative stress triggers include a poor diet, low physical activity, prolonged stress, and intrinsic factors, such as mitochondrial dysfunction leading to reduced adenosine 5-triphosphate (ATP) production, inflammation, and hypoxia (106, 117)