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Genotoxicity As a direct consequence of a reduction in carcinogenic toxicant emission, cMRTP aerosols should display significantly reduced mutagenicity and genotoxicity in standard cell-based assays, such as the Ames, in vitro micronucleus and the mouse lymphoma assays [32, 50]

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Though cigarette usage has been on the decline in the state of Pennsylvania, the increase in nicotine vaping has dramatically increased in the past few years

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