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Authorities say that the drug effect [of nicotine] tends to require increasing use, to tie one up to it, to make it difficult to get along without it. It is agreed that even in what is called moderation in tobacco using, whenever there is an unusual strain put upon the circulatory system the heart is apparently less efficient. Some smokers consume 50 cigarettes a day

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Try repositioning them to minimize this effect

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For instance, tobacco-related diagnosis, such as tobacco use disorder or history of tobacco use, are insensitive in estimating the prevalence of current and past smokers, but have a high specificity [10, 12,13,14]