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Gum and lozenges: Buccal absorption similar to pouches, but with more user control over dosing
One example is the subunit vaccine against hepatitis B, which is composed of only the surface proteins of the virus (previously extracted from the blood serum of chronically infected patients but now produced by recombination of the viral genes into yeast)
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The wrapper adds a hint of natural sweetness, but the main event here is the tobacco itself
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