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"Nicotine is not the most harmful part of cigarettes nicotine is a major reason that cigarettes are addictive," said Theodore Wagener, director of the Center for Tobacco Research and co-leader of the Cancer Control Research Program at The Ohio State University Comprehensive Cancer Center

Reductions in lung cancer mortality in economically developed countries reflect decreased incidence (mirroring declines in tobacco smoking) and improvements in treatment of patients with advanced-stage disease, including immunotherapies and targeted therapies

Similar trends were observed in urban areas (2008: 1.81%, 2013: 4.61%

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