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As bupropion is an antidepressant, it would also be useful to look further at whether people with past or current depression are more likely to quit smoking when using it, especially considering that there may be an increased risk of mental health side effects

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DOI: 10.1001/jamanetworkopen.2022.0951 The study was supported by grant P30 CA14599 from the University of Chicago Medicine Comprehensive Cancer Center, the Global Research Award for Nicotine Dependence from Pfizer and the Womens Board of the University of Chicago Cancer Research Foundation

A key factor in evaluating the proposals merits and justification must inevitably be one of efficacy: Will it actually work