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Because ribosome biogenesis is a complex process requiring tight coordination of ribosomal RNA and ribosomal protein production 35 , our data implicates potential imbalance of rRNA and ribosome protein synthesis by e-cig exposure, thereby leading to disruption of ribosome biogenesis

Country-specific trajectories and heatmap analysis A detailed heatmap analysis of Bahrains smoking mortality by age group from 1990 to 2019 (Figure 4) revealed persistently high death rates among individuals aged 70 years, particularly in the early 2000s when values exceeded 1900/100000

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