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In addition, Kyn is able to induce and activate AhR and thereby upregulates PD1 expression in CD8 + T cells

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All 529 compounds were also determined to be present in the smoke of the 3R4F reference cigarette, with only a minority of the compounds being present in THS2.2 aerosol at concentrations exceeding those measured in the smoke of the 3R4F reference cigarette