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Abstract Despite the association between tobacco use and the harmful effects on general health as well as male fertility parameters, smoking remains globally prevalent

Nicotine is the most harmful: Nicotene which is the end product of tobacco causes release of dopamine inthe brain which encourages neurotransmission resulting in craving

Nicotine should never be taken by adolescents, pregnant women or people with heart conditions The best choice any smoker can make is to quit cigarettes and nicotine use altogether

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