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Some of the aberrations in brain energy metabolism associated with bipolar disorder are similar to the metabolic phenotype displayed by cells lacking CaMKK2

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Test tube studies shows that ALCAR donates a acetyl group to help make acetylcholine.[iii] Alzheimers-diseased brains show a 25% to 40% reduction in carnitine acetyltransferase , an enzyme that works with L-Carnitine & Acetyl-L-Carnitine

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